3D cell culture – a new dimension for cell culture

We have developed a unique and novel 3D cell culture system that supports and promotes neural cell growth in a true 3 dimensional fashion. We call it Bioactive3D.

Bioactive3D (patent pending) consists of a cell friendly coated, electrospun random fibre scaffold, which provides a cell culture matrix that supports the growth of neural cells with truly 3-dimensional morphologies. This improved cell culture method leads to cell morphologies resembling the true in vivo cell morphology and preserves the cell metabolism and protein expression in a way which is closer to in vivo than any existing standard 2D system can provide. Primary astrocyte cultures when grown on Bioactive3D, for example, not only develop complex in vivo like morphologies, but also grow under minimal stress conditions, whilst being fully responsive to reactivity triggering stimuli.